Per Bolus contains
 Metronidazole BP 2 gm

 Metronidazole is an antibiotic that is used commonly to treat protozoal infections and anaerobic bacterial infections. It also has anti-inflammatory effects in the bowl. Metronidazole is bactericidal; it kills bacterial microorganisms by disrupting their DNA. It is absorbed rapidly from the GI tract, metabolized by the liver and excreted in the urine and the feces. Because metronidazole only has activity against anaerobic bacteria. It is used commonly with other antibiotics when it is used to treat mixed bacterial infections. It is compatible with many other antibiotics including penicillin antibiotics, aminoglycosides and some cephalosprins.

 Metronidazole is used primarily with other antibiotics to treat mixed-bacterial infections in which anaerobic bacteria are present, for example, pleuropneumonia, peritonitis and abdominal abscesses. It also is used prophylactically after colic or other abdominal surgery when mixed bacterial infections are a risk.
 Metronidazole is used to treat protozoal infections in dogs and cats including Giardia, Entamoeba, Trichomonas and Balantidium.

Side Effects:
 Most common clinical signs related to the bad taste or GI upset.
 Excessive salivation, gagging, regurgitation, pawing at the mouth, nausea, vomiting and decreased appetite are the most frequent complaints.

 Metronidazole causes birth defects in laboratory animals. It should be avoided in pregnant animals, especially in the first trimester. Some metronidazole is excreted in breast milk and it should not be used in lactating animals.
 Metronidazole should not be used in young puppies and kittens.
 Metronidazole should be avoided or used with caution, at reduced doses, in animals with kidney or liver diseases.

Drug Interactions:
 Metronidazole is reported to elevate prothrombin time in animals on warfarin or other coumarin anticoagulants.

Dosage and Administration:
 20 mg for per kg bodyweight for 10-12 days.

Storage Conditions:
 Store in a cool and dry place, protected from light.
 Keep all medicines out of reach of children.

 4x5’s bolus in a Box.